Clinical efficacy of platelet rich plasma (PRP) on healing of intrabony defects treated with xenograft– a case report

Introduction: The main goal in the treatment of intrabony defects is the regeneration of the lost attachment apparatus and the restoration of function and aesthetics in the affected area. In the available scientific literature various therapeutic modalities for the treatment of the latter have been described, but a few studies assess the beneficial properties of platelet-rich plasma (PRP) as an adjunct in the healing process. The present case report proved the clinical efficacy of PRP when added to xenograft (Bio-Oss®) in case of periodontal intrabony defect. Bovine-derived xenograft has been identified as an osteoconductive and biocompatible grafting material. PRP has been demonstrated to release polypeptide growth factors gradually over at least 1 week. The letter have the ability to enhance wound healing and to improve clinical benefits of bone replacement grafts. 
Purpose: The main purpose of this case report is to highlight the successful clinical performance of PRP used as an adjunctive tool for regeneration in intrabony periodontal defects using xenograft.

Materials and methods: The therapeutic approach include using of xenograft (Bio-Oss®) and PRP for the treatment of three wall intrabony defect was establish using cone-beam computed tomography (CBCT).

Results: Achieving satisfactory functional and aesthetic results and in maintaining the stability of the regenerated bone at 6 month follow-up.

Conclusion: Xenograft combined with PRP can be successfully treatment approach used for treatment of intra-bony defects. 

Dr. Lilia Kavlakova